Future long-term space exploration missions require the implementation of circular life support systems for the supply of water, oxygen and food from mission wastes.Therefore, separation systems dealing with multi-phasic streams need to be addressed.The BioHarvest (BHV) study focused on solid/liquid separation in space with the aim to demonstrate t
Objective To explore factors that potentially impact external validation performance while developing and validating a prognostic model for hospital admissions (HAs) in complex older general practice patients.Study design and setting Using individual participant data from four cluster-randomised trials conducted in the Netherlands and Germany, we u
Transcriptional signatures are an indispensible source of correlative information on disease-related molecular alterations on a genome-wide level.Numerous candidate genes involved in disease moondrop quarks and in factors of predictive, as well as of prognostic, value have been deduced from such molecular portraits, e.g.in cancer.However, mechanist